BACKGROUND: Intrauterine bladder rupture is a rare complication usually caused by structural bladder outlet obstruction. Some medications are known to cause urinary retention or diuresis in fetuses and preterm infants. CASE: A 31-year-old gravida 6, para 3023 at 29 weeks and 2 days’ gestation required intubation, mechanical ventilation, and medical management for severe chest pain and respiratory failure, eventually diagnosed as asthma and pneumonia. An obstetrical ultrasound on hospital day three revealed a markedly dilated fetal bladder. Repeat ultrasound the following day showed a decompressed fetal bladder and significant ascites. A cesarean delivery was performed for a nonreassuring fetal heart rate. Postnatal evaluation by voiding cystourethrogram and cystoscopy revealed bladder rupture without evidence of outlet obstruction. Given the absence of other plausible causes, the rupture was likely due to exposure to maternal medications. CONCLUSION: Transplacental exposure to maternal medications may cause fetal urinary retention and intrauterine bladder rupture. Fetal ultrasound surveillance during treatment with medications known to cause urinary retention may allow for early diagnosis and intervention.
PDF] Medication induced fetal bladder rupture: a case report
Cureus, Luteoma of Pregnancy Presenting as Ruptured Ectopic Pregnancy: A Case Report
Fetal Bladder Rupture as a Complication of Adjunctive Therapy in
Aminotic Fluid Index and its Correlation with Fetal Growth and Perinatal Outcome
Case Based Pediatrics Chapter
A very rare fetal complication due to obstructive uropathy - ScholarMD
JCM, Free Full-Text
Radiation and chemotherapy induced cystitis, Radiology Reference Article
Open retropubic prostatectomy in a patient with bladder exstrophy for management of hematuria and urethral discharge – A case report - ScienceDirect
Prenatal ultrasound showing an enlarged fetal bladder.
PDF) Exposure to biological maternal sounds improves
Full article: Fetal Bladder Rupture as a Complication of Adjunctive Therapy in Severe Maternal SARS-CoV-2 Pneumonia
Frontiers Case Report: Abruptio placentae and epileptic seizure after occurrence of perinatal hyperglycaemia in woman with gestational diabetes mellitus and hypertriglyceridemia-induced acute pancreatitis
Suzuka Okuno's research works University of Tsukuba, Tsukuba and
PDF) Exposure to biological maternal sounds improves