The pathway heatmap is an appealing visualization to clearly shows how the expression of each pathway gene compares to the others. It is generated when you click a pathway or gene set name in the “Gene Set Enrichment” panel at the result page. An example output is shown below The pathway heatmap values are calculated through a series of steps: The fitted model for each gene is evaluated across the range of doses in the uploaded data. The resulting modeled expression values are normalized
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Nextcast: A software suite to analyse and model toxicogenomics