3D Shape of an Ion Channel Revealed Memorial Sloan Kettering Cancer Center

Structural biologist Stephen Long talks about how his team used x-ray crystallography to discover the structure of an ion channel called K2P1.

Cryo-EM structure of the calcium release-activated calcium channel Orai in an open conformation

Structural titration reveals Ca2+-dependent conformational landscape of the IP3 receptor

Bone-matrix mineralization dampens integrin-mediated mechanosignalling and metastatic progression in breast cancer

Memorial Sloan Kettering Cancer Center — JDP Mechanical

Alexandria N. Miller Sloan Kettering Institute

Memorial Sloan Kettering Cancer Center, The Mortimer B. Zuckerman Research Center - Work - ZGF

Structural titration reveals Ca2+-dependent conformational landscape of the IP3 receptor

RCSB PDB - 6WCB: Human open state TMEM175 in CsCl

Kai XU, Memorial Sloan Kettering Cancer Center, New York City, MSKCC, Division of Structural Biology

PDF) 3D clusters of somatic mutations in cancer reveal numerous rare mutations as functional targets

RCSB PDB - 8GKA: Human TRPV3 tetramer structure, closed conformation

Three-dimensional imaging mass cytometry for highly multiplexed molecular and cellular mapping of tissues and the tumor microenvironment

Differential ion dehydration energetics explains selectivity in the non-canonical lysosomal K+ channel TMEM175