Researchers at the Broad Institute of MIT and Harvard and Massachusetts General Hospital have constructed a high-resolution cellular map of Crohn
Researchers at the Broad Institute of MIT and Harvard and Massachusetts General Hospital have constructed a high-resolution cellular map of Crohn's disease, a chronic condition in which a hyperactive immune system causes inflammation throughout the gut, leading to symptoms including abdominal pain, diarrhea, and weight loss. The disease is difficult to treat and often requires hospitalization.
Newer Biologic and Small-Molecule Therapies for Inflammatory Bowel Disease
Meta-analysis defines predominant shared microbial responses in various diseases and a specific inflammatory bowel disease signal, Genome Biology
Inflammatory bowel disease
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Persistence of Lgr5+ colonic epithelial stem cells in mouse models of inflammatory bowel disease
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single cell analysis of fecal washes reveals diverse cell type
Single-cell analysis of Crohn's disease reveals a detailed picture